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Search Results for " g protein-coupled bile acid receptor 1 "

13

Compounds

Cat No. Product Name Synonyms Targets
T5077 Deoxycholic acid sodium salt Sodium deoxycholate,Sodium Desoxycholate Endogenous Metabolite , GPCR19
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T2965 Deoxycholic acid Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic Endogenous Metabolite , GPCR19
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio...
T7428 SBI-115 GPCR19
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T4083 BAR501 BAR 501 GPCR19
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
TQ0252 BAR502 FXR , GPCR19 , Autophagy
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T4352 SB756050 SB-756050,SB 756050 GPCR19
SB756050 is a specific TGR5 agonist.
T0700 Ursodeoxycholic acid UDCA,Ursodiol Potassium Channel , Endogenous Metabolite
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T8818 TC-G 1005 GPCR19
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
T2968 Hyodeoxycholic acid NSC 60672,α-Hyodeoxycholic Acid,HDCA FXR , Endogenous Metabolite , GPCR19
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
T1824 TGR5 Receptor Agonist GPCR19
TGR5 is a potent TGR5(GPCR19) agonist.
T29078 Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium FXR , Endogenous Metabolite , GPCR19
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...
T63554 TGR5 Receptor Agonist 3
TGR5 Receptor Agonist 3 is a G protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist soft drug compound that decreases gallbladder filling, exhibits good gallbladder safety, and is able to act on hTGR5 (EC50: 16.4 ...
T60439 CAY10789
CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 μM. CAY10789 is also a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 μM. CAY10789 s...
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